Background: The creation of glide path reduces the risk of instrument breakage. Glide path is created before using NiTi rotary instrumentation Aim: This study compared the changes in the root canal anatomy after creation of glide path using Path Files (PF) and V Glide Path 2 (VGP2) using Cone Beam Computed Tomography (CBCT). Materials and Methods:Hundred extracted mandibular first molars with curved mesial roots, curvature angles ranging within 20-30 degrees were assigned into two groups (n = 50 each). Glide path was prepared using PF (Group I) and VGP2 (Group II). CBCT images were obtained before and after instrumentation. The technical outcomes were compared at 0, 1, 2, 3, 5 and 7mm intervals. The data was analyzed using t-test and Chi-square test.

The aim of this study was to describe canal anatomy modifications by Path Files (PF) using cone beam computed tomography (CBCT) in mandibular first molars. A total of 100 mesiobuccal (MB) root canals of mandibular first molars were prepared with PF. CBCT was used to scan the specimens before and after instrumentation. The root canal curvature, centric ability, apical transportation, root canal cross sectional area and canal volume were measured. Changes in canal anatomy modifications were recorded at 0, 1, 2, 3, 5 and 7mm intervals. There was a statistical difference in the root canal curvatures between the pre and post instrumented samples (P < 0.05). There was no transportation at 5mm , all the canals were transported towards the distal side except there was a slight mesial transportation at 0mm. They exhibited good centric ability at all the intervals except at 1mm (P > 0.05). The difference in the cross sectional area was also statistically significant at all the intervals (P < 0.05).The changes in the volume were statistically significant at all the intervals except at 3 mm (P > 0.05).