Background: Traumatic spinal cord injury (TSCI) can cause numerous adverse effects on the spinal cord and neural tissues. These injuries may have negative effects on physical and psychological health during the lifespan. Objectives: The present study aimed to investigate the epidemiology of TSCI in patients with trauma admitted to Bessat Hospital of Hamadan between 2007 and 2017. Methods: A cross-sectional study was conducted on 3,219 patients with traumatic spinal injuries admitted to Bessat Hospital of Hamadan between 2007 and 2017. Data were collected from the hospital information system. Data analysis was performed using SPSS. Quantitative data were expressed as mean, standard deviation, and frequency, and qualitative data were analyzed using the chi-square and Fisher's exact tests. The significance level was considered to be less than 0.05. Results: Mortality was significantly associated with gender (P = 0.001), age (P = 0.051), external causes of injury (P = 0.001), and type of injury (P = 0.001). The length of hospital stay was significantly associated with the type of injury (P = 0.001) and external causes of injury (P = 0.001), whereas there was no significant relationship between the length of hospital stay and gender, age, and surgery (P > 0.05). Conclusions: Mortality rates were highest at the age of 55 years or over among other age groups. Thus, effective interventions and programs should be implemented for this age group.
Background and Objectives: Colorectal Cancer (CRC) is the fourth cancer-related cause of death worldwide. CRC is a multi-stage cancer, which is curable during the early stages of the disease. Therefore, determining the time of cut-point existence could improve treatment planning and help directly allocate resources. This study aims to determine the cut point in the age of CRC diagnosis. Methods: This study, covering the course 1985 to 2012, consisted of 345 colorectal cancer patients registered in Taleghani Hospital, Tehran, Iran and followed up to 2013. The cut-point in the age of CRC diagnosis was obtained using a mixture cure model. The data were analyzed using SPSS and R, V. 20 and 2.15.0, respectively. Results: The results showed that the cut point in the age of CRC diagnosis was 50 years. Based on our estimation, 65% of the patients diagnosed with CRC at or younger than 50 were cured, while 31% of them diagnosed older than 50 were cured, and the younger group had a better survival over the older group. Conclusion: Since access to a cut-point and analysis of created prognostic groups are important in screening and treatment planning, our results suggested that it is better to estimate the cut-point in the age of curable cancers in early stages via survival cure models, and the cure rate would increase by CRC timely screening.
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