Background: An infant should be able to coordinate sucking, swallowing, and breathing to have a safe and effective feeding, which is developed with the increasing gestational age. Any problem in each of these functions can lead to the risk of aspiration, pneumonia, decreased oxygenation saturation, apnea, and bradycardia. The changed body positions may cause changes in the physiological efficiencies of the preterm infants. The objective of this review is to determine the impact of body position on the physiological alternations in the preterm infants while bottle feeding. Methods: In order to review the previous studies, we referred the related resources from existing databases such as Scopus,