BACKGROUND: Postoperative adhesion is an important complication after middle-ear surgeries. Although many materials have been tried to prevent this complication, the use of Poly ( dl -lactide ε-caprolactone) as an anti-adhesive material after middle-ear surgery has not yet been reported. The aim of this study was to evaluate the anti-adhesive effect of poly ( dl -lactide ε-caprolactone) on the ears of rats with middle-ear mucosa damage. Methods: In our study, 14 Wistar albino rats and 28 ears in total were used. The rats were randomly divided into 4 groups. Middle ear mucosa damage was performed in all groups with a transcanal approach under otomicroscopy in sterile conditions. The effects of poly ( dl -lactide ε-caprolactone), silicone sheet, and absorbable gelatin sponge were compared histologically with the secondary healing group. In addition, hearing evaluation was performed before the procedure and on the 28th postoperative day. Results: No significant difference was observed in transient otoacoustic emission and distortion product otoacoustic emissions tests performed before and after the surgical procedure when the groups were compared. While adhesion was observed in the tympanic membrane in the absorbable gelatin sponge group, no adhesion was observed in the other groups. In the absorbable gelatin sponge group, increased fibroblastic activity, inflammation, and neovascularization were observed in the middle-ear mucosa. No significant difference was observed in silicone sheet, poly ( dl -lactide ε-caprolactone), and control groups in terms of fibroblastic activity, inflammation, and neovascularization. Conclusion: It can be concluded that absorbable poly ( dl -lactide ε-caprolactone) is nonototoxic and biocompatible with the rat's middle ear cavity by short-term evaluation.

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toacariasis is the infestation of the external ear canal with mites or ticks. Although it is more commonly seen in the external ear canal of animals, it can rarely be seen in the external ear canal of human beings. Mite infestation in the external ear canal is rarely observed compared to tick infestation. The cases of otoacariasis caused by tick were reported in South Africa, Chile, Malaysia, Sri Lanka, America and Turkey.