Novel coronavirus disease 2019 (COVID-19) outbreak has termed as a controllable pandemic, and the entire world has come to a standstill trying to mitigate the disease with health systems. Health care providers, around the globe, are fighting day and night. Currently, rapid testing is taking place with the help of nasopharyngeal, oropharyngeal swab, bronchoalveolar lavage, sputum, urine, and blood. All these approaches are invasive or embarrassing to the infected person. It is observed that salivary glands are hosting severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2) because of angiotensin-converting enzyme 2 and the detection of high viral loads in the saliva and is playing a crucial role in virus transmission, especially from individuals showing absolutely no symptoms. Saliva is proving to be a promising noninvasive sample specimen for the diagnosis of COVID-19, thus helping to monitor the infection and prevent it from further spreading by prompt isolation.

No abstract

The aims of this in vitro study were to evaluate the effect of enamel fluorosis on the shear bond strength (SBS) of orthodontic brackets and to determine whether adhesion promoter, Enhance LC, increases the bond strength of brackets to fluorosed enamel. Forty-five (30 fluorosed and 15 non-fluorosed) non-carious fresh human premolar teeth, extracted for orthodontic reasons and without any caries or visible defects, were used in this study. The fluorosed teeth were selected according to the modified Thylstrup and Fejerskov index, which is based on the clinical changes in fluorosed teeth. In groups 1 (fluorosed teeth) and 3 (control), the brackets were bonded with Light Bond composite resin and cured with a halogen light. In group 2, Enhance LC was applied to fluorosed enamel before bonding. After bonding, the SBS of the brackets was tested with a universal testing machine. One-way analysis of variance and Tukey multiple comparison tests were used to compare the SBS of the groups. Any adhesive remaining after debonding was assessed and scored according to the modified adhesive remnant index. The results showed that while fluorosis significantly reduced the bond strengths of the orthodontic brackets (mean 13.94 +/- 3.24 MPa; P < 0.01), Enhance LC significantly increased bond strength on fluorosed enamel (mean 18.22 +/- 5.97 Mpa; P < 0.05). Groups 1 and 3 had greater bond failures at the composite-bracket interface, whereas group 2 showed bond failure primarily at the enamel-composite interface.

Because bleaching and desensitizer application significantly affected shear bond strengths of orthodontic brackets on human enamel, they should be delayed until the completion of orthodontic treatment.

This case report presents an unusual maxillary right first molar with four roots and six canals. Endodontic treatment was provided and final restoration was accomplished with composite resin. Treating extra canals in maxillary first molars may be challenging. Inability to find and properly treat the root canals may cause failures. Complete clinical and radiographic examination and a thorough knowledge of the morphology of these teeth is necessary for successful clinical results.