Temporomandibular joint (TMJ) involvement in rheumatoid arthritis (RA) patients has been described in the literature; however, its incidence varies greatly. The current study aimed to determine the prevalence and clinical characteristics of TMJ involvement in RA patients. This cross-sectional study consisted of 60 individuals with RA. The patients were assigned to two groups, those with TMJ involvement and those without TMJ involvement. TMJ involvement was defined based on the findings of questionnaires and clinical examinations by a rheumatologist. The symptoms and signs were recorded by a single trained dentist. The mean age of patients was 43.9 ± 15.52 years (range: 21-78 years), and the majority of the participants were women (n = 49, 81.66%). Thirty-five patients (58.3%) had clinical evidence of TMJ involvement. The levels of C-reactive protein (CRP) (P value= 0.01) and rheumatoid factor (RF) (P value = 0.02) were found to be correlated with TMJ involvement (). There was no significant correlation between TMJ involvement and erythrocyte sedimentation rate (ESR), age, gender, treatment duration, or disease duration. This study showed a high level of CRP in RA patients with TMJ involvement. The results further showed a significant correlation between TMJ involvement and RF. TMJ pain was reported in almost half of the RA patients.