Anterior segment eye parameters are essential factors in diagnosis, screening and management of abnormal ocular conditions. Based on the previous studies, they might differ from one race or population to another. Sistan-and-Baluchestan province, the southeast of Iran, has special weather conditions and race, plus lack of research on these diagnostic factors. Hence, the objective of the present study was to assess anterior segment parameters using pentacam in this area. 800 eyes of subjects which had been referred to the Al-Zahra eye hospital of Zahedan, the capital city of the province, for corneal refractive surgery from October 2014 to March 2015 participated in this research. 95% confidence limits for mean of central corneal thickness, anterior chamber depth and volume were (536.02, 541.20), (3.13, 3.18) and (187.63, 192.58) respectively. Multiple linear regression models showed a lower mean central corneal thickness, and maximum/minimum of keratometry, for males than females, adjusting for age and spherical equivalent. Inversely, anterior chamber depth, and volume were more in males. In order to diagnosis and treating ocular diseases which have effect on retinal thickness, precisely specification of predictive factors is highly needed.

<p>Retinal nerve fiber layer thickness is an important factor in early diagnosis of posterior pole dysfunctions, assessment of treatment effect, and disease progress. The aim of this study was to compare the macular and peripapillary retinal thickness between genders and among refractive error types in healthy subjects. In addition, effective determinants of the thickness were ascertained. This cross-sectional study was conducted on 58 subjects (116 eyes), which had been referred to the Toos eye clinic of Mashhad, northeast of Iran, for refractive error surgery from September 2012 to June 2013. We used Optical Coherence Tomography for retinal thickness measurements. The mean±SD spherical equivalence was estimated to be -2.06±0.36 dioptres (range: -11.50, 7.38), axial length 23.89±0.14 mm, average peripapillary thickness 89.91±0.94 μm, average macular thickness 274.68±1.84 μm, and overall macular volume 9.89±0.07 mm³.Multiple linear regression modeling was indicated that axial length and gender had significant effect on average macular thickness. Axial length also showed substantial effect on average peripapillary thickness. Retinal thickness measurement regardless of refractive error type could lead to bias in disease diagnosis. The results of the present study might be used to enhance the assessment precision of ocular diseases.</p>

No abstract

Background & Aims: Retinal nerve fiber layer thickness is an important factor in the early diagnosis of posterior pole dysfunctions, assessment of treatment effect, and disease progression. The aim of this study was to compare the macular and peripapillary retinal thickness between genders and among refractive error types in healthy subjects. In addition, effective determinants of the thickness were ascertained. Materials & Methods:This cross-sectional study was conducted on 58 subjects (116 eyes) who were referred to the Toos eye clinic of Mashhad, northeast of Iran, for refractive error surgery and their caregivers in 2014. We used Optical Coherence Tomography for retinal thickness measurements. Results: The mean age was 26.02±0.42 years. The mean±SD spherical equivalence was estimated to be -2.06 ± 0.36 dioptres, axial length was 23.89 ± 0.14 mm, average peripapillary thickness was 89.91 ± 0.94 μm, average macular thickness was 274.68 ± 1.84 μm, and overall macular volume was 9.89 ± 0.07 mm3. Multiple linear regression modeling indicated that axial length and gender had a significant effect on average macular thickness. Axial length also showed a substantial effect on average peripapillary thickness. Conclusion:Retinal thickness measurement regardless of refractive error type could lead to bias in disease diagnosis. The results of the present study might be used to enhance the assessment precision of ocular diseases.