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IntroductionOveractive bladder (OAB) is one of the most common complications in patients with multiple sclerosis (MS). Choosing the effective treatment is very important in improving their quality of life (QOL). Therefore, the aim of this study was to compare solifenacin (SS) and posterior tibial nerve stimulation (PTNS) treatment effects in the MS Patients with OAB.Materials and methodsIn total, 70 MS patients suffering from OAB enrolled in this clinical trial study. Patients with a score of at least 3 according to the OAB questionnaire were randomly divided into two groups (35 patients in each group). In one group, patients received SS (5 mg daily for 4 weeks and 10 mg/day for another 8 weeks) and in a second group, patients were treated by PTNS (12 weekly session, 30 min).ResultsThe mean (SD) age of patients participating in this study was 39.82 (9.088) and 42.41 (9.175) years for the SS group and the PTNS group, respectively. Patients in both groups showed statistically significant improvements in urinary incontinence, micturition, and daytime frequency (p < 0.001). Patients in the SS group had a better response for urinary incontinence after 12 weeks compared to the PTNS group. Also, patients in the SS group reported higher satisfaction and less daytime frequency compared to the PTNS group.ConclusionSS and PTNS were effective for improving the OAB symptoms in patients with MS. However, patients demonstrated a better experience with SS in terms of daytime frequency, urinary incontinence, and treatment satisfaction rate.

Background. Excessive and early lumbopelvic motion during functional tasks is associated with increased pain and symptoms in people with low back pain. The purpose of the current study was to compare lumbopelvic and lower extremity movements in two subgroups of chronic low back pain sufferers and healthy subjects during a stair descending task based on a movement system impairment model. Material and methods. A clinical examination was conducted to assign people with low back pain to movement system impairment-based subgroups. A control group included 18 healthy subjects, a lumbar Rotation with Flexion group included 12 subjects, and a lumbar Rotation with Extension group included 16 subjects. Differences in kinematics data between the groups were recorded during a stair descending task using a 7-camera 3-dimensional motion capture system. Results. In the lumbar Rotation with Flexion group, the onset of lumbar movement occurred earlier than in the control group (p = 0.043). In the lumbar Rotation with Flexion group, axial and frontal plane rotation of the pelvis and lower extremity were significantly greater than in the control group. Mean differences between the lumbar Rotation with Extension and control group were minimal for the motion assessed. Conclusion. Early and excessive lumbopelvic movement and more axial rotation in the lower extremities during a stair descending task were found in the lumbar Rotation with Flexion subgroup, which can be an important factor contributing to the development or persistence of low back pain in this group.