Original Research ArticleHematological changes in pregnancy induced hypertension in their third trimester at ABSTRACT Background: Pregnancy induced hypertension (PIH) is one of the most common and potential life-threatening complications of pregnancy. This study is aimed to investigate and correlate the hemoglobin, haematocrit, white blood cell count, lymphocytes and platelets in PIH patients in their third trimester. Method: Total 126 subjects were studied out of them 63 patients (case) and 63 healthy pregnant women (control) visiting the Obstetrics and Gynaecology department Jhalawar Medical College, Jhalawar were registered in the study and followed during their pregnancy. Two millilitre of blood sample was drawn aseptically using the 5ml syringe from the median ante cubital vein of all the cases and control participants into EDTA-anticoagulated tubes. Haematological parameter calculated by using Sysmex XN-9100™ Automated Haematology System. Results: The mean hemoglobin level of the case group (8.8206±2.53779) was significantly lower than that of the control group (9.7289±2.47033) (p<0.05). The mean platelet count of the case group (131.4937±62.05999) was significantly lower than that of the control group (324.9683±230.78764) (p<0.05). The mean lymphocytes level of case group (1.2510±0.56369) was significantly lower than that of the control group (1.9295±1.4150) (p<0.05). The mean WBC level of case group (36.3467±119.90635) was significantly high than control group (11.5260±4.83059) (p<0.05). The mean haematocrit level of case group (32.6851±7.29789) was significantly high than control group (30.0424±23.38116) (p<0.05). Conclusion: The mean hemoglobin, mean platelets and mean lymphocytes are lower in PIH patients. The mean WBC and haematocrit are higher in PIH patient.

Background: Hysterectomy is one of the most common gynaecological surgeries performed worldwide. The common indications for hysterectomy are benign like symptomatic uterine leiomyomas, endometriosis etc. We compare clinico-surgical outcome of vaginal hysterectomy with hydro dissection versus without hydro dissection. Methods: Women attending Gynae OPD or admitted was included in study and 30 cases taken in each group. Group A: Vaginal hysterectomy with hydro dissection. Hydro Dissection was done by about 50 ml to 100 ml of saline was infiltrated under pressure all around the cervix, just under vaginal mucosa below the bladder sulcus. Group B: Vaginal hysterectomy without hydro dissection. Results: The mean age of cases in Group-A was 49.63±8.91 yrs and in Group-B was 48.03±5.39 yrs was uniform. The mean operative time in Group-A was 49.07±6.46 min and in Group-B was 53.40±5.87 min which was statistically significant (p-value = 0.009). The mean intraoperative blood loss in Group-A was 89.77±6.49 ml and in Group-B was 97.67±12.93 ml which was statistically significant (p-value = 0.005). The mean level of change in Hb was 0.70±0.29 gm/dl in Group-A and was 1.01 ± 0.43 gm/dl in Group-B, which was statistically significant (p-value = 0.002). Conclusions: Hydro dissection with saline in vaginal hysterectomy is associated with significant reduction in duration of surgery, blood loss and lower mean level of change in Hb.