A series of biologically active phenoxy derivatives of 2-substituted benzoxazole organophosphates have been synthesized by the reaction of S-(benzoxazolyl-2)phosphorodichloridothioate/phosphorodichloridodithioate with phenol/4-chlorophenol/4-nitrophenol in 1:1 and 1:2 molar ratio. These compounds have been characterized by elemental analysis, IR, 1 H NMR, and 31 P NMR spectral studies. The antibacterial activity of these 2-substituted benzoxazolephenoxy derivatives has been evaluated against pathogenic bacteria Staphylococcus aureus (+ve) and Escherichia coli (-ve). The antifungal activity of these 2-substituted benzoxazolephenoxy derivatives has been evaluated against pathogenic fungi Aspergillusniger and Fusariumoxysporium. All the compounds were found to have moderate antibacterial and antifungal activity.
Background: Pulmonary infections are among the most common infections encountered in outpatient and inpatient clinical care. The most useful imaging modalities available for the evaluation of the patient with suspected pulmonary infection are chest radiography and computed tomography (CT).The aim of present study is to evaluate various patterns of pulmonary disease depicted radio logically and to establish and compare sensitivity and specificity of radiography and computed tomography. 64.66 % and 75% respectively with PPV and NPV of 98.68% and 6.82% respectively. CT scan showed Sensitivity, Specificity, PPV and NPV of 87.10%, 98.89 %, 96.43% and 95.70% respectively for the diagnosis of pyogenic bacterial infections, Sensitivity, Specificity, PPV and NPV of 95.70 %, 97.87 %, 98.63% and 95.83 % respectively for the diagnosis of mycobacterial infections and Sensitivity, Specificity, PPV and NPV of 93.33%, 99.06 %, 93.33% and 99.06 Materials and Methods: This prospective observational study included a total of 120 patients with suspected pulmonary infections referred for chest imaging. Chest radiography examination was done in all the patients. Subsequently all of the patients underwent either contrast enhanced and/or non contrast high resolution computed tomography of the chest as appropriate on 128 slice Philips Multi-detector CT (MDCT). Imaging finds were interpreted independently and tabulated and subsequently correlated with clinical and pathological findings. Results: Most of the patients were in the 51 to 60 years age group (29.2%) with male predominance (55%). Sensitivity and specificity of chest X-ray in detection of pulmonary infections was
As a result of the Covid-19 pandemic, working from home (WFH) was introduced wherever it was possible around the world. For working parents (employees with at least one dependent child), it was not simply WFH, but it also included challenges related to a new way of learning from home for their children. The pandemic changed the way people worked in organisations; we’ve all had to adjust our daily routines to cope with it and we are still learning how to do so. The aim of this study was to investigate the experiences of working parents and examine the factors that contributed to their resilience while working from home during New Zealand’s first lockdown in March–April 2020. Ten in-depth, semistructured interviews were undertaken with working parents (having at least one school-aged child) drawn from sectors such as banking, education and professional services in the Wellington region. Data was analysed using a thematic analysis approach. Study results highlight that WFH was effective in enabling business continuity facilitated by virtual tools. However, participants reported high levels of stress as a result of uncertainty due to the pandemic and balancing work–family life, which had a negative impact on their performance and productivity. The key implication for organisations is to be mindful of the unique needs and challenges that working parents face when working from home. They need to nurture a culture of empathy while providing the right work set-up, including the use of virtual tools to connect and collaborate for WFH effectiveness. The study provides insight into the experiences of working parents and possible factors that contribute to resilience during a pandemic.
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