The innovation of wearable devices is advancing rapidly. Activity monitors can be used to improve the total hip replacement (THR) patients’ recovery process and reduce costs. This systematic review assessed the body-worn accelerometers used in studies to enhance the rehabilitation process and monitor THR patients. Electronic databases such as Cochrane Database of Systematic Reviews library, CINAHL CompleteVR, Science Citation Index, and MedlineVR from January 2000 to January 2022 were searched. Due to inclusion criteria, fourteen eligible studies that utilised commercial wearable technology to monitor physical activity both before and after THR were identified. Their evidence quality was assessed with RoB 2.0 and ROBINS-I. This study demonstrates that wearable device technology might be feasible to predict, monitor, and detect physical activity following THR. They could be used as a motivational tool to increase patients’ mobility and enhance the recovery process. Also, wearable activity monitors could provide a better insight into the individual’s activity level in contrast to subjective self-reported questionnaires. However, they have some limitations, and further evidence is needed to establish this technology as the primary device in THR rehabilitation.

Background Several investigations have demonstrated that vitamins can be used to treat or prevent cancer by altering actin filaments, inhibiting cell migration and cancer cell proliferation. Vitamins D and E are fat-soluble. This research aims to determine the short-term impact of vitamin D and E on the mechanical characteristics of breast cancer cells before comparing them with normal breast cells. Method Atomic force microscopy (AFM) was used to examine the deformation of MCF-10 normal breast cells, MCF-7 breast cancer cells, and MCF-7 breast cancer cells treated with 0.03 µM vitamin D and 16 µM vitamin E solution. Young's modulus was calculated employing the Hertz model to determine cell stiffness. Results The Young's modulus of vitamin D-treated cancer cells (585.8 Pa) was substantially similar to that of normal cells (455.6 Pa). Nevertheless, vitamin E treatment had no effect on Young's modulus of cancer cells, which remained remarkably similar to that of untreated cancer cells (216.6 and 203.4 Pa, respectively). Conclusion Despite vitamin E, vitamin D enhances the stiffness of tumor cells and puts their mechanical characteristics similar to normal cells by interfering with actin filaments and cell skeletons, which may inhibit tumor cell migration. According to these findings, Vitamin D appears to be an effective drug for cancer treatment.