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The diagnostic accuracy of the I 3M to assess the legal age of 18 years has already been tested in several specific-population samples. The left lower third molar has been extensively used for discriminating between minors and adults. This research aimed to compare the usefulness of lower third molar maturity indexes, from both left and right side (I 3M L and I 3M R), in samples originating from four distinct continents in order to examine possible differences in their accuracy values. For this purpose, a sample of 10,181 orthopantomograms (OPGs), from Europe, Africa, Asia and America, was analysed and previously scored in other studies. The samples included healthy subjects with no systemic disorders with both third molars and clear depicted root apices. Wilcoxon Signed Rank test for left and right asymmetry did not show any significant differences. Data about sensitivity, specificity, predictive values, likelihood ratio and accuracy were pooled together and showed similar results for I 3M L and I 3M R, respectively. In addition, all these quantities were high when only the I 3M R was considered to discriminate between adults and minors. The present referable database was the first to pool third molar measurements using panoramic radiographs of subjects coming from different continents. The results highlighted that both I 3M L and I 3M R are reliable indicators for assessing the legal age of 18 years old in those jurisdictions where this legal threshold has been set as the age of majority.

Objective: To assess dental age and deviations of dental from chronological age according to the Willems and Cameriere methods (European formula) in patients with cleft lip and/or cleft palate (CL/P) and compare it with control group. Design: Retrospective cross-sectional study. Setting: Clinic of Orthodontics. Participants: Sixty-nine patients with CL/P between 6 and 15 years of age (55 with unilateral and 14 with bilateral CL/P) with 148 panoramic radiographs. The same number of radiographs was examined in the age-matched control group. Main Outcome Measures: Estimation and comparison of dental age and differences of dental from chronological age in relation to the type of cleft, sex, and age in the group of patients with and without CL/P according to Willems and Cameriere method. Results: No significant intersex and intergroup differences were found in deviations of dental from chronological age according to Cameriere method ( P > .05). Significant difference in deviation of dental from chronological age was found between the patients with and without CL/P according to Willems method ( P < .001). Conclusion: Cameriere European formula for dental age estimation, which is not influenced by sex and tooth morphology, showed similar dental development of children with and without CL/P. However, Willems method detected that deviation of dental from chronological age significantly differed between children with and without clefts.

Introduction/Objective. The class II malocclusion results in disbalanced facial harmony, primarily noticeable in the profile and the lower facial third. Aside from skeletal evaluation, orthodontic diagnosis and treatment planning should include facial soft tissue analysis. The aim of the study was to identify the soft tissue profile outcomes of orthodontic treatment of Class II, division 1 malocclusion patients and to determine if these changes are related with the different treatment protocol. Methods. The first group was the non-extraction group (25 patients) treated first with the Herbst appliance, and the second group was four premolars extraction group (25 patients) treated with a multibracket appliance. The patients? cephalograms and pre- and post-treatment profile photographs were used. Results. The improvement in the non-extraction group was evident in the decrease of the nasomental angle, the angle representing the projection of the upper lip to the chin, as well as the upper lip angle. In the extraction group, the nasolabial angle showed a significant increase. Soft tissue variables showed significant differences between the groups: the total facial angle or facial convexity including the nose and the angle presenting the projection of the upper lip to chin. Conclusion. The patients treated without extractions showed a significant improvement of the convex profile and favorable soft tissue changes in the lower third of the face.