There were used the spherical lenses in industry conventional for long time, but new types of lenses were created during innovation processes. One type of lenses is aspherical. Two main parameters describing quality of aspherical lenses are accuracy of the form shape and surface roughness. These parameters can be obtained after last operation – polishing. Technical parameters that give the biggest influence to form shape and surface roughness were investigated in this experiment and optimal technical parameters for polishing process were established. Melted quartz ,,UVFS” was used in this research, investigations were carried out according by full factorial design. Five axis CNC machine Schneider SCPA100 was used for polishing and profilometer Nanoscan 855 was used for measurements. After analysis of results it was found out that speed of rotation and penetration depth are the most important factors in polishing process. For getting the best shape it’s necessary to use the smallest chosen values of speed of rotation and penetration depth, for getting the best surface roughness polishing parameters changing conversely. The smallest value of surface roughness Rz was 0.06 µm, and shape deviation was 2.6 µm. Optimal polishing parameters for the best quality of aspherical lenses was provided.