Background: Extended-spectrum β-lactamases (ESBLs) are enzymes capable of hydrolyzing oxyimino-β-lactams and inducing resistance to third generation cephalosporins. The genes encoding ESBLs are widespread and generally located on highly transmissible resistance plasmids. We aimed to investigate the complement of ESBL genes in E. coli and Klebsiella pneumoniae causing nosocomial infections in hospitals in Ho Chi Minh City, Vietnam. Methodology: Thirty-two non-duplicate isolates of E. coli and Klebsiella pneumoniae causing nosocomial infections, isolated between March and June 2010, were subjected to antimicrobial susceptibility testing. All isolates were PCR-amplified to detect the bla SHV , bla TEM and bla CTX-M ESBL genes and subjected to plasmid analysis. Results: We found that co-resistance to multiple antimicrobials was highly prevalent, and we report the predominance of the bla CTX-M-15 and bla CTX-M-27 genes, located on highly transmissible plasmids ranging from 50 to 170 kb in size. Conclusions: Our study represents a snap shot of ESBL-producing enteric bacteria causing nosocomial infections in this setting. We suggest that antimicrobial resistance in nosocomial E. coli and Klebsiella pneumoniae is rampant in Vietnam and ESBL organisms are widespread. In view of these data and the dramatic levels of antimicrobial resistance reported in Vietnam we advocate an urgent review of antimicrobial use in the Vietnamese healthcare system.
It is well known that estuarine systems are significantly affected by hydrodynamic conditions such as river discharge, storm surges, waves and tidal conditions. In addition to this, human interferences through developmental projects have the capability of disrupting the natural morphological processes occurring at estuaries. In West Africa, the goal to improve standards of living through large-scale dam construction, offshore ports and coastal erosion countermeasures has triggered alarming changes in the morphodynamics of estuarine systems. The estuaries at the Volta River mouth (Ghana) and “Bouche du Roi” inlet (Benin), located along the Bight of Benin coast, West Africa, were selected as two case study sites to examine their long-term morphodynamics and sandspit evolution. In this study, we primarily analyzed estuarine morphology using remotely sensed images acquired from 1984 to 2020. We further estimated the longshore sediment transport for this region using results from the image analysis and the depth of active sediment motion. Our results reveal that the longshore sediment transport rates for this region are in the magnitude of 105–106 m3/year. Comparative analysis with other estuaries and sandy coasts suggests that the longshore sediment transport along this coast has one of the largest rates estimated in the world.
The Nobiru Coast is situated on the southwest of the Ishinomaki Bay. The 2011 Great East Japan Tsunami severely devastated the Nobiru Coast and the adjacent Naruse River mouth. In this study, an investigation was conducted based on the available historic maps and images combined with in situ surveys that revealed the century-to-decade morphology change and sediment budget alteration in the Nobiru Coast. During the past two centuries, the longshore transport on the northeast coast and sediment supply from the Naruse River were the principal sediment supply onto the Nobiru Coast and the estimated annual net sediment input into the coast was 87,000 m3/y. Until several decades ago, the construction of the Ishinomaki Port and the erosion preventing constructions (breakwaters, headlands) along the Ohmagari Coast on the northeast areas caused a dramatic reduction of longshore transport to the Nobiru Coast. Hence, the net sediment input fell to 46,000 m3/y. After the tsunami, the sediment input was further reduced to 29,000 m3/y and this loss was closely related to the intruded sediment into the Naruse River. The outcomes of this study are highly valuable for the government authorities to manage the long-term coastal and riverine morphological changes after the 2011 tsunami.
On 11 March 2011, the Great East Japan Earthquake generated huge tsunami waves. Then, tsunami propagation occurred in rivers, resulting in further expansion of the flooded area. Full data sets of tsunami characteristics such as tsunami inland and river propagation distances as well as the river geometries from all rivers within the Tohoku District were compiled and analyzed. It was found that tsunami propagation distance in rivers was about 1.2 to 4.5 times that of the inland area. There was a good correlation between propagation distance in rivers and the river bed slope. Furthermore, new empirical formulae for calculating the damping coefficient of tsunami wave height and tsunami intrusion length were successfully derived based on the current comprehensive data sets covering a wide range of river geometry and bottom slope. Moreover, tsunami-induced flow discharge was evaluated by using measured water level variation.
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