Tuberculosis is still a worldwide public health concern especially in developing countries. Extrapulmonary tuberculosis including abdominal tuberculosis is known as the great mimicker and usually delayed due to its nonspecific clinical presentation. A-30 years old male patient presented to our hospital with 5-months history of persistent lower right-sided abdominal pain, anorexia, and weight loss. Computed tomography scan of the abdomen suggested malignant mass of ascending colon. Chest x-ray showed suprahilar right lung fibro-infiltrates suggested lung tuberculosis. Colonoscopy was performed which revealed tumor of the hepatica flexure Biopsy was taken from colonoscopy showed non-specific colitis results. Surgery was performed due to suspicious of ascending colon malignancy. Histopathological evaluation of colon biopsy revealed features of caseating granulomas and Langerhans giant cells that consistent with tuberculosis. A diagnosis of colonic tuberculosis was concluded and the patient is treated with anti-tuberculosis drug regimens.

Lung cancer with symptomatic small intestinal metastasis is a rare case but potentially fatal with poor diagnosis in most advanced stages. A-82 years old male patient with chronic cough, chest pain, progressive dyspnea abdominal pain, obstipation, and distended abdomen. Chest computed tomography (CT)-scan revealed right inferior pulmonary lobe of lung tumor. Abdominal X-ray and abdominal ultrasound showed ileus obstruction features. The patient underwent emergency laparotomy under the diagnosis of total ileus obstruction. Surgical resection of two masses in the small intestinal were performed with ileo-ileal anastomosis. Histomorphology of the surgical specimen revealed poorly differentiated adenocarcinoma involving the small intestine without precursor lesions that suggested a metastasis. The patient underwent thoracentesis and pleural fluid cytology that reported seeding of non-small cell lung cancer (NSCLC) tend to adenocarcinoma type. A diagnosis of lung adenocarcinoma with small intestinal metastasis was concluded based on correlation of these anatomopathological examination. Clinicians should consider possibility of lung cancer with small intestinal metastasis in patient with abdominal symptoms.