Background: Convalescent plasma therapy (CPT) is one of the methods used in treatment in COVID-19, but the administration of CPT to COVID-19 patients is still controversial. This study aims to assess the difference in survival between CPT administration in severe-critical COVID-19 patients and standard therapy. Methods: This research was a retrospective cohort observational research. Survival analysis was carried out on the factor and outcome variables by estimating the median survival time and Kaplan-Meier survival curve.