Background: Grown-up congenital heart disease (GUCH) patients are unique and challenges especially at developing country. The numbers of diagnostic as well as interventional cardiac catheterization procedures in GUCH patients are growing. The aim of this study was to report the outcome of cardiac catheterization including intervention procedure in GUCH.Methods: The descriptive study was conducted at Sanglah Hospital, Denpasar, Bali, Indonesia. All patients (age of more than 12 years) who underwent cardiac catheterization from 2011 until 2017 were included in this study. Patients, characteristic, types of catheter procedures, immediate complications, and outcomes were documented.Results: A total 54 subjects were included with median age of 23 years and 70% were female. The first symptom that brought patients to hospital is dyspnea 46% and palpitation 32%. Five subjects underwent a diagnostic catheter procedure and 49 (91%) diagnostic and catheter based interventions. Transcatheter interventions procedures included atrial septal defect (ASD) (success rate of 20 per 21), patent ductus arteriosus (PDA) (success rate of 16 per16), ventricular septal defect (VSD) (success rate of  9 per 9), pulmonal stenosis (PS) (success rate of 1 per 2), and aortic stenosis (AS) (success rate of 1 per 1). The complications encountered were transient dysrhythmias in 15 subjects, device embolization in 4 subjects, massive bleeding in 1 subject, and overall mortality in 2 subjects.Conclusion: The number of the catheterization interventions in GUCH was 91% and ASD device closure was the most common procedure. Transcatheter intervention has a high procedural success rates (96%) and low procedural-related complications.

Background: Heart failure is a clinical syndrome due to decreased cardiac output affecting body perfusion, including the kidneys. An acute or chronic relationship between the heart and the kidney is called cardiorenal syndrome. Cardiorenal syndrome worsens the clinical state and prognosis of patients with heart failure. This study aimed to analyse correlation heart failure score and estimate GFR based on cystatin C.Methods: This cross-sectional with a study subject of children aged 0-12 years with a diagnosis of heart failure caused by congenital and acquired heart disease. The data were recruited consecutively in the children emergency room with the period January 2016 to July 2017. The decrease in cardiac output was enforced based on cardiac failure score according to modification of Ross when arrived at the hospital and followed by determining the estimated GFR based on cysC base on formula 75.94/CysC1.178 mg/dl. Correlation between heart failure score and estimated GFR was tested using Spearman correlation.Results: Forty-one subjects were analysed, had median heart failure score 10 (minimum/min 7, maximum/max 12). Median estimate GFR based on cysC 81.65 (min 12.31, max 133.23) ml/minute/1.73m2. There was a moderate negative association between heart failure score and estimated GFR based on cystatin C (r= -0.53; p<0.001).Conclusion: A moderate negative correlation between heart failure score and estimated glomerular filtration rate based on cystatin C levels in children.Â

BackgroundIn the past, cardiovascular involvement did not seem to be a common complication of HIV, but in recent years it has been described more frequently. With the advent of highly active antiretroviral therapy (HAART), the symptoms of cardiac disease has changed, as the number of HIV-infected patients with abnormal diastolic parameters has increased significantly, often presenting as symptomatic rather than asymptomatic. Objective To analyze for a possible correlation between HAART duration and left ventricular diastolic function in HIV-infected children.Methods This cross-sectional study was conducted from . Subjects with HAART were collected using a consecutive sampling method. The following data were recorded for each subject: age, sex, current stage of HIV, CD4+ level, as well as HAART regimen and duration of use. Transthoracic echocardiography was performed for tissue doppler imaging (TDI) of diastolic function. Spearman's test was used to analyze the strength of correlation based on normality test results. Results This study involved 53 subjects, 21 of whom had impaired diastolic function. There was no correlation between HAART duration and diastolic function in children with HIV infection (r= -0.03; P=0.82). Conclusion Diastolic dysfunction is found in children under HAART treatment, but there is no correlation between HAART treatment duration and diastolic dysfunction. [Paediatr Indones. 2019;59:139-43; doi: http://dx.doi.