Wetlands are critically important for biodiversity and human wellbeing, but face a range of challenges. This is especially true in the Mediterranean region, where wetlands support endemic and threatened species and remain integral to human societies, but have been severely degraded in recent decades. Here, in order to raise awareness of future challenges and opportunities for Mediterranean wetlands, and to inform proactive research and management, we identified (a) 50 key issues that might affect Mediterranean wetlands between 2020 and 2050, and (b) 50 important research questions that, if answered, would have the greatest impact on the conservation of Mediterranean wetlands between 2020 and 2050. We gathered ideas through an online survey and review of recent literature. A diverse assessment panel prioritised ideas through an iterative, anonymised, Delphi-like process of scoring, voting and discussion. The prioritised issues included some that are already well known but likely to have a large impact on Mediterranean wetlands in the next 30 years (e.g. the accumulation of dams and reservoirs, plastic pollution and weak governance), and some that are currently overlooked in the context of Mediterranean wetlands (e.g. increasing desalination capacity and development of antimicrobial resistance). Questions largely focused on how best to carry out conservation interventions, or understanding the impacts of threats to inform conservation decision-making. This analysis will support research, policy and practice related to environmental conservation and sustainable development in the Mediterranean, and provides a model for similar analyses elsewhere in the world.

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Integrated Nature CultuRE Approach (INCREAte) promotes the interconnection of culture and nature. this approach primarily targeted toward nature conservation managers but is also applicable to any agent working on nature-culture issues or area and resource management. The focus of this approach is to guide users to design more integrated and efficient conservation projects by working on issues related to culture while also addressing stakeholders' participation and human wellbeing. Allowing users to be selective and flexible, such issues can also be incorporated in ongoing projects, making the INCREAte approach a practice-oriented guidance and toolkit rather than a "take it or leave it" option. It was developed by the Scientific Secretariat of the Mediterranean Institute for Nature and Anthropos (MedINA) that, since 2003, promotes joint management of natural and cultural heritage and the strengthening of the diachronic relationship between humankind and nature. This approach has been successfully tested in Kythera, where a strategy for tourism has been designed through a sequence of its relevant steps. The main focus of the strategy is the development of an integrated and innovative trail network, which, coupled with the accompanying activities of the programme, is designed to reveal and sustain the natural and cultural heritage of the island.