Systemic EBV positive T-cell lymphoma of childhood (S-EBV-TCL) is a rare disease for which there is no standard of care. S-EBV-TCL is often associated with hemophagocytic lymphohistiocytosis (HLH) and is generally thought of on the spectrum of Epstein-Barr Virus (EBV) related disease. For the few reported cases of cure in the literature, hematopoietic stem cell transplant (HSCT) has been required. Here, we present the case of one patient who was successfully cured with a modified regimen of dose adjusted EPOCH (etoposide, prednisone, vincristine, cyclophosphamide, doxorubicin), followed by HSCT using a reduced intensity conditioning regimen.

Neonatal compartment syndrome, although rare, has a classic presentation with sentinel skin findings and subsequent development of swelling, erythema, and tenderness of the affected extremity. Neonatal compartment syndrome requires prompt surgical intervention to preserve the affected limb and ensure its normal growth and development. Our patient was born at term via vaginal delivery complicated by a compound presentation involving the left upper extremity. No physical exam abnormalities were noted at birth, but she developed signs of neonatal compartment syndrome by 15 hours of life. She was surgically treated at 22 hours of life and recovered well. At one year of age, she has normal growth and function of the affected extremity. Our case adds to the growing literature associating neonatal compartment syndrome with a compound fetal presentation.