Beta-range oscillatory activity measured over the motor cortex and beta synchrony between cortex and spinal cord can be up- or downregulated in anticipation of a postural challenge or the initiation of movement. Based on these properties of beta activity in the preparation for future events, the present investigation addressed whether simultaneous up- and downregulation of beta activity might act as an online mechanism to suppress and select competing responses. Measures of local and long-range beta synchrony were obtained from electroencephalographic and electromyographic signals recorded during a cued choice reaction task. Analyses focused on task-related changes in beta synchrony during a 2-s delay period between cue and response signal. Analyzed separately, none of the beta measures (spectral power, corticospinal coherence, corticospinal phase synchronization) showed simultaneous up- and downregulation over opposite hemispheres controlling the competing responses. However, the combined pattern of beta measures showed beta power desynchronization associated with selection of a response and increased corticospinal coherence and phase synchronization associated with suppression of a response. These results indicate that concurrent up- and downregulation of different components of beta oscillatory activity is likely to have a functional role in response selection, resembling attentional modulation of alpha activity in visual selection.

This paper validates a novel instrumented object, the iBox, dedicated to the analysis of grasping and manipulation. This instrumented box can be grasped and manipulated, is fitted with an Inertial Measurement Unit (IMU) and can sense the force applied on each side and transmits measured force, acceleration and orientation data wirelessly in real time. The iBox also provides simple access to data for analysing human motor control features such as the coordination between grasping and lifting forces and complex manipulation patterns. A set of grasping and manipulation experiments was conducted with 6 hemiparetic patients and 5 healthy control subjects. Measures made of the forces, kinematics and dynamics are developed, which can be used to analyse grasping and contribute to assessment in patients. Quantitative measurements provided by the iBox reveal numerous characteristics of the grasping strategies and function in patients: variations in the completion time, changes in the force distribution on the object and grasping force levels, difficulties to adjust the level of applied forces to the task and to maintain it, along with movement smoothness decrease and pathological tremor.

Previous behavioral work has shown the existence of both anticipatory and reactive grip force responses to predictable load perturbations, but how the brain implements anticipatory control remains unclear. Here we recorded electroencephalographs while participants were subjected to predictable and unpredictable external load perturbations. Participants used precision grip to maintain the position of an object perturbed by load force pulses. The load perturbations were either distributed randomly over an interval 700- to 4,300-ms (unpredictable condition) or they were periodic with interval 2,000 ms (predictable condition). Preparation for the predictable load perturbation was manifested in slow preparatory brain potentials and in electromyographic and force signals recorded concurrently. Preparation modulated the long-latency reflex elicited by load perturbations with a higher amplitude reflex response for unpredictable compared with predictable perturbations. Importantly, this modulation was also reflected in the amplitude of sensorimotor cortex potentials just preceding the long-latency reflex. Together, these results support a transcortical pathway for the long-latency reflex and a central modulation of the reflex grip force response.

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This paper presents a novel robotic interface to investigate the neuromechanical control of redundant planar arm movements. A unique aspect of this device is the third axis by which the wrist, and hence the pose of the arm can be fully constrained. The topology is based on a 5R, closed loop pantograph, with a decoupled wrist flexion/extension cable actuated mechanism. The design and characterization (in terms of range of motion, impedance, friction and dynamics) are described in this paper. This device is lightweight, safe and has high force capabilities and low impedance. Simple experiments illustrate the advantages of this device for the investigation of redundant motor control in humans.