Background The optimal pain therapy for children undergoing tonsillotomy remains unknown. Our aim was to evaluate a standard pain therapy including the alternating application of ibuprofen and paracetamol. Methods Pain intensity of 81 in‐patients after tonsillotomy aged 2–12 years was evaluated three times daily (mean observation 3.85 days) using the Children's and Infants’ Postoperative Pain Scale (CHIPPS) in children <5 years, or with the Faces Pain Scale‐Revised (FPS‐R) in older children. Parents completed the Parents’ Postoperative Pain Measure (PPPM‐D) in addition. Exceeding the cut‐off value in one of the scores implied the indication for an opioid rescue medication (RM). Endpoints were number of children with indication for the RM, course of pain, concordance between pain scales, and adverse events. Results Overall, 45.7% of children needed the RM either in the recovery room or on the ward. The rate of children having an indication for RM on the ward was 30.9%. The highest proportion of affected children was identified on the day of surgery (32.1%). Most indications were detected with the PPPM‐D only. A comparison with an earlier study showed less affected children compared to ibuprofen monotherapy on the day of surgery and the first postoperative day. Eleven children (13.6%) developed fever. Conclusion Although our pain therapy concept was effective from postoperative day 1 onwards, it needs improvement for the day of surgery. The overall concordance between the PPPM‐D and CHIPPS or FPS‐R was low. Fever might be a confounder for the pain intensity measurement with the PPPM‐D.