Scoliosis is a condition defined by an abnormal spinal curvature. For diagnosis and treatment planning of scoliosis, spinal curvature can be estimated using Cobb angles. We propose an automated method for the estimation of Cobb angles from X-ray scans. First, the centerline of the spine was segmented using a cascade of two convolutional neural networks. After smoothing the centerline, Cobb angles were automatically estimated using the derivative of the centerline. We evaluated the results using the mean absolute error and the average symmetric mean absolute percentage error between the manual assessment by experts and the automated predictions. For optimization, we used 609 X-ray scans from the London Health Sciences Center, and for evaluation, we participated in the international challenge "Accurate Automated Spinal Curvature Estimation, MICCAI 2019" (100 scans). On the challenge's test set, we obtained an average symmetric mean absolute percentage error of 22.96.

Anomaly detection is a widely explored domain in machine learning. Many models are proposed in the literature, and compared through different metrics measured on various datasets. The most popular metrics used to compare performances are F1-score, AUC and AVPR. In this paper, we show that F1-score and AVPR are highly sensitive to the contamination rate. One consequence is that it is possible to artificially increase their values by modifying the train-test split procedure. This leads to misleading comparisons between algorithms in the literature, especially when the evaluation protocol is not well detailed. Moreover, we show that the F1-score and the AVPR cannot be used to compare performances on different datasets as they do not reflect the intrinsic difficulty of modeling such data. Based on these observations, we claim that F1-score and AVPR should not be used as metrics for anomaly detection. We recommend a generic evaluation procedure for unsupervised anomaly detection, including the use of other metrics such as the AUC, which are more robust to arbitrary choices in the evaluation protocol.

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