Several tokamaks structures containing 500 keV protons to be used in P-B11 fusion were simulated. In order to find the optimal confinement configuration, the simulation was helped by an evolutionary algorithm running 145,000 simulations. The results are presented in this paper. According to the simulations the tokamak structure can be operated to reach ignition using the proposed plasma mode that includes the use of low electron temperature and high thermal energy protons in the plasma (500 keV).