The Suzuki-Miyaura cross-coupling of potassium aryland heteroaryltrifluoroborates with aryl-and heteroaryl triflates is reported. The catalyst system provides good to excellent yields using sterically hindered and electronically diverse coupling partners.

2005 C-C bond formation O 0282Palladium-Catalyzed Suzuki-Miyaura Reactions of Potassium Aryl-and Heteroaryltrifluoroborates with Aryl-and Heteroaryl Triflates. -The Suzuki--Miyaura cross-coupling of sterically hindered and electronically diverse aryl triflates with potassium aryl-and hetaryltrifluoroborates is readily achieved using a Pd(O-Ac)2 PCy3 catalytic combination. -(MOLANDER*, G. A.; PETRILLO, D. E.; LANDZBERG, N. R.; ROHANNA, J. C.; BIOLATTO, B.; Synlett 2005, 11, 1763-1766; Dep. Chem., Univ. Pa., Philadelphia, PA 19104, USA; Eng.) -Mais 48-050