:The aim of the paper was the evaluation of the modifications of the retinal nerve fiber layer for the patients with primary open angle glaucoma or ocular hypertension associated with diabetes mellitus. Material and method: a prospective study that included a number of 25 patients. The study group was made up of 17 patients: 12 patients with primary open angle glaucoma (POAG) and diabetes mellitus and 5 patients with ocular hypertension (OH) and diabetes mellitus. The control group included 8 patients without glaucoma. All the patients with an accurate diagnosis of primary open angle glaucoma and intraocular hypertension that were medically and/or surgically treated or not, associated with diabetes mellitus, were included in the study. The patients with other types of glaucoma (closed angle, pigmentary, cortisone related, pseudoexfoliative), the ones without an accurate diagnosis of glaucoma or without associated diabetes mellitus were excluded. The control group was made up of subjects without a glaucoma diagnosis or clinical elements related to glaucoma, without surgical interventions in their medical records. All participants were evaluated with CIRRUS HD-OCT.
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