An overview is given of ISO results on regions of high excitation ISM and gas, i.e. H II regions, the Galactic Centre and Supernova Remnants. IR emission due to fine-structure lines, molecular hydrogen, silicates, polycyclic aromatic hydrocarbons and dust are summarised, their diagnostic capabilities illustrated and their implications highlighted.

Abstract. An overview is given of ISO results on regions of high excitation ISM and gas, i.e. H ii regions, the Galactic Centre and Supernovae Remnants. IR emission due to fine-structure lines, molecular hydrogen, silicates, polycyclic aromatic hydrocarbons and dust are summarised, their diagnostic capabilities illustrated and their implications highlighted.