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BackgroundTo investigate whether the combination of anastrozole and Tualang honey (T honey) influences background parenchymal enhancement (BPE) in breast magnetic resonance imaging (MRI) of postmenopausal women with breast cancer.MethodsA total of 30 patients were recruited and randomly divided into control (anastrozole 1 mg daily) and intervention (anastrozole 1 mg + T honey 20 g daily). The BPE of the contralateral breast before and six months following treatment was compared using the sign test.ResultsThere was a decrease in BPE in 10% of the women (p = 0.317) who received only anastrozole, which resulted in a change of BPE category from moderate to mild. However, the combination of anastrozole and T honey evoked a decrease in BPE in 42% of the patients (p = 0.034).ConclusionsThe combination of T honey and anastrozole maybe more efficacious than anastrozole alone in decreasing breast BPE in breast cancer patients. These findings support the medicinal value of T honey as an adjuvant treatment to anastrozole.

Abstract:We proposed an expert system based on the interpretation of mammographic and ultrasound images that may be used by expert and non-expert doctors in the interpretation and classifying of patient cases. The expert system software consists of a mammographic(MAMMEX) and breast ultrasound(SOUNDEX) medical expert systems which may be used to deduce cases according to the Breast Imaging Recording and Data System (BI-RADS) based upon patients' history, physical and clinical assessment as well as mammograms and breast ultrasound images. The systems were tested on a total of 179 retrospective cases from the Radiology Department, Hospital Universiti Sains Malaysia (HUSM), Kubang Kerian, Kelantan. The accuracy, sensitivity and specificity of MAMMEX were 97%, 96% and 92% and values of 99%, 98% and 100% were found for SOUNDEX respectively.

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