Background: Nutrition education is one method to change the knowledge and attittude of nutrition on school children.The study aimed to see the effect of nutrition education on knowledge and attitude of nutrition among school children.Methods: The study was one group pre-post test design of a quasi experimental design. Subjects were 99 schoolchildren randomly selected through multi stage sampling method among the 4th, 5th, and 6th graders. They were givennutrition education using posters and pocket books in children meeting for three months. The data of knowledge andattitude were collected through interview using structure questionares. The differences in knowledge attitude andpractice of of nutrition among school children were tested by wilcoxon test.Results: The mean of knowledge about nutrition among school children before nutrition education is 66,45±9,6%increasing to 71,61±9,3% after nutrition education. Median of attitude before nutrition education is 70,31% increasingto 75% after nutrition education. The result showed that there was an effect of nutrition education on knowledge andattitude of school children.Conclusion: Nutrition education can improve knowledge and attitude of school children.

BackgroundThis study aims to evaluate the association and dose-response between triglyceride-glucose (TyG) index and breast cancer.MethodThis is a multicenter case-control study conducted in six public referral hospitals in Indonesia. Cases are individuals aged 19 years or above who were diagnosed with breast cancer within 1 year of diagnosis, based on histopathology and immunohistochemistry. Controls were recruited from corresponding hospitals. TyG index was determined by the formula: ln (fasting TG [mg/dl] × fasting glucose [mg/dl]).ResultsThere were 212 participants in the breast cancer group and 212 participants in the control group. TyG index was higher in patients with breast cancer (median 8.65 [7.38, 10.9] vs. 8.30 [7.09, 10.84], p < 0.001). When compared with TyG quartile of Q1, Q4 was associated with an OR of 2.42 (1.77, 3.31), p < 0.001, Q3 was associated with an OR of 1.53 (1.21, 1.93), p < 0.001, Q2 was associated with an OR of 1.39 (1.12, 1.73), p = 0.002 for the risk of breast cancer. The dose-response relationship was nonlinear (p < 0.001). On univariate analysis, smoking (OR 2.15 [1.44, 3.22], p < 0.001), use of contraception (1.73 [1.15, 2.60], p = 0.008), alcohol consumption (OR 2.04 [0.96, 4.35], p = 0.064), and TyG Index >8.87 (OR 3.08 [1.93, 4.93], p < 0.001) were associated with risk of breast cancer. Independently associated with increased risk of breast cancer included smoking (OR 1.93 [1.23, 3.01], p = 0.004), use of contraception (OR 1.59 [1.02, 2.48], p = 0.039), and TyG Index >8.87 (OR 2.93 [1.72, 4.98], p < 0.001)ConclusionTyG index was associated with breast cancer in a nonlinear dose-response fashion.

Latar belakang. Angka kesakitan diare pada balita di negara berkembang masih tinggi. Pada beberapa penelitian terbukti efek seng dan probiotik masing masing dalam mencegah diare dapat menurunkan angka kejadian. Namun pemberian secara bersamaan belum banyak diketahui. Tujuan. Membuktikan pengaruh suplementasi seng dan probiotik secara bersamaan pasca perawatan diare akut pada anak terhadap kejadian diare berulang. Metode. Penelitian kohort prospektif lanjutan Studi I "Pengaruh suplementasi seng dan probiotik terhadap durasi diare akut cair anak", selama 3 bulan. Subjek adalah 75 anak usia 6-24 bulan pasca rawat diare akut cair di RS Dr. Kariadi Semarang. Pengelompokkan dilakukan secara acak menjadi 4 kelompok, kelompok I hanya mendapat terapi baku tanpa suplementasi, kelompok II mendapat suplementasi seng, kelompok III diberikan suplementasi probiotik, dan kelompok IV kombinasi seng-probiotik. Setiap kelompok mendapat terapi baku, rehidrasi, dan dietetik. Uji statistik menggunakan analisis kesintasan untuk mengetahui kejadian diare berulang, uji Kruskal Wallis untuk perbedaan frekuensi dan lama diare. Hasil. Kelompok suplementasi seng-probiotik bersamaan memiliki rerata survival diare berulang terlama yaitu 10,94 minggu (CI 95% 9,24 -12,65), dibanding kelompok lainnya, meskipun secara statistik tidak berbeda bermakna (p=0,892). Frekuensi maupun lama diare berulang keempat kelompok pada bulan pertama, kedua dan ketiga pasca suplementasi secara statistik tidak berbeda bermakna. Kesimpulan. Pemberian suplementasi seng-probiotik bersamaan berpengaruh dalam memberikan rerata perlindungan terhadap terjadinya diare berulang lebih lama. Tidak terdapat perbedaan bermakna dalam rerata survival diare berulang, lama dan frekuensi diare berulang di antara keempat kelompok. Sari Pediatri 2011;13(2):96-104.Kata kunci: suplementasi seng, probiotik, diare berulang