Objectives : To study COVID‐19 (Delta Variant) cases and close contacts co‐located within households. Focusing on epidemiology of transmission of COVID‐19, quarantine duration and utilisation of infection control behaviours under a telehealth model of care in an elimination setting. Methods : A retrospective cohort analysis examined household spread of infection, duration of quarantine and change in PCR CT value during illness. A survey explored infection control behaviours used by household members during isolation and quarantine. Results : The cohort was 141 individuals in 35 households. Thirty‐seven were index cases, and 48 became positive during quarantine, most within 10 days. Whole‐household infection occurred in 12 households with multiple members. Behaviours focused on fomite transmission reduction rather than preventing aerosol transmission. The median duration of close contact household quarantine was 25 days. The majority of COVID‐19 cases were de‐isolated after 14 days with no evidence of further community transmission. Conclusion : Intrahousehold transmission was not universal and, if it occurred, usually occurred quickly. Behaviours utilised focused on fomites, suggesting a need for improved education regarding the potential utilisation of strategies to prevention the transmission of aerosols. Households experienced long durations of home‐based quarantine. Implications for public health : The impact of long quarantine durations must be considered, particularly where most community benefit from quarantine is achieved within 10 days from exposure in the setting of the Delta Variant. Education of households regarding aerosol risk reduction is a potential strategy in the household setting of individuals at risk of disease progression.

Background: Long COVID, or post-COVID-19 sequelae, is being seen in a growing number of patients reporting a constellation of symptoms, both pulmonary and extrapulmonary. Studies on COVID-19 recovered patients are scarce. Thus, there is a need to add granularity to our existing knowledge about the course and long-term effects of the infection. Aim: To describe the clinical details and risk factors of post-COVID sequelae in the North Indian population. Method: This prospective observational study was conducted at a tertiary healthcare centre in Northern India between October 2020 to February 2021. Patients aged >18 years with a confirmed COVID-19 disease were recruited after at least two weeks of diagnosis and interviewed for any post-COVID-19 symptoms. Results: Of 1234 patients recruited, who were followed up for a median duration of 91 days (IQR: 45-181 days), 495 (40.11%) patients had symptoms. In 223 (18.1%) patients, the symptoms resolved within four weeks, 150 (12.1%) patients had symptoms till twelve weeks, and 122 (9.9%) patients had symptoms beyond twelve weeks of diagnosis of COVID-19. Most common long COVID-19 symptoms included myalgia (10.9%), fatigue (5.5%), shortness of breath (6.1%), cough (2.1%), disturbed sleep (1.4%), mood disturbances (0.48%) and anxiety (0.6%). The major determinants of developing post-COVID-19 symptoms in the patients were hypothyroidism and the severity of the disease. Conclusion: Most often, patients complain of myalgias, fatigue, dyspnoea, cough and disturbed sleep. Patients who are hypothyroid or have recovered from moderate to severe COVID-19 are at higher risk of developing post-COVID sequelae. Therefore, a multidisciplinary approach is required to diagnose and manage COVID-19 recovered patients.

Aplastic anemia is usually associated with hemorrhagic stroke. Here, we report a case of ischemic stroke secondary to aplastic anemia in a 28-year-old male who presented with sudden-onset right hemiplegia and aphasia when he was not on any immunosuppression for five months. His laboratory findings showed pancytopenia, and his peripheral blood smear showed no atypical cells. Magnetic resonance imaging of the brain with magnetic resonance angiography (MRA) of the neck and brain vessels revealed an infarct in the left cerebral hemisphere in the middle cerebral artery territory, and no significant stenosis or aneurysm was observed on MRA. The patient was managed conservatively and discharged in stable condition.

Background: With COVID-19 becoming a major worldwide cause of concern, it is important to understand the various manifestations of the disease in order to fully manage it. Neurological manifestations of COVID-19 assume great importance because of considerable mortality and morbidity both during the disease and recovery. The following review aims to shed light on impact of COVID -19 on neurological system. Common neurological manifestations have been described. With more people surviving the disease, post-COVID syndrome has become a prominent ailment. A note is also made of the impact introduction of vaccines for COVID-19. Finally, the epidemic of -black fungus‖ or Mucormycosis has also been touched upon. Neurological manifestations:The most important neurological manifestations are stroke, encephalitis, encephalopathy and myelitis on the central nervous system and Guillain-Barre Syndrome (GBS) and chronic muscle fatigues on the peripheral nervous system.Mucormycosis: With a decline in number of cases of COVID-19, the deadly epidemic of mucormycosis has resurged. It is characterized by involvement of sinuses, eye and brain. Early recognition and treatment can prevent many complications.