Background The COVID-19 pandemic has drastically affected everyone in a hit or miss manner. Since it began, evidence of the neuro-invasive potential of the virus has been intensifying significantly. Several pathways have been hypothesized to elucidate the neurotropic nature of SARS-CoV2. It is the need of the hour to collect vital information. Objective To evaluate and correlate the neuro-radiological and neurological manifestations in patients diagnosed with SARS-CoV2. To identify neuro-invasive pathways of COVID infection. Methods Relevant studies were identified through four databases—the Cochrane Library, PubMed, Science Direct, and Web of Science. These were searched using relevant keywords—“COVID-19,” “SARS-CoV2,” “neurological manifestations,” “neuroimaging,” “CT,” and “MRI.” Relevant articles were screened according to a pre-defined inclusion and exclusion criteria from December 2019 to August 2020. Results Our review included a total of 63 full text publications with 584 patients, composed mainly of observational studies, case reports, and case series. The most common neurological manifestations associated with COVID-19 were altered mental status, stroke, and paralysis. About 17.85% patients who underwent neuroimaging were found to be having ischemic changes suggestive of a stroke. This was followed by hemorrhagic changes as the second most common finding. The most commonly involved vessel was the Middle Cerebral Artery. Besides stroke, we found that SARS-CoV2 could be the cause for new-onset seizures, Guillain-Barre Syndrome, encephalitis, and many other severe neurological diseases. Conclusion The information that we have obtained so far will prove dynamic to healthcare providers working against the COVID-19 pandemic. It is necessary to be aware of these atypical neurological findings for the early diagnosis and treatment of COVID-19 infected patients. However, to completely understand the connection between SARS-CoV2 and the nervous system, further research is necessary.
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The global pandemic has shaken the foundational notions that characterize modern society. A host of rights that dignify our life have had to be sacrificed, with the new ‘normal’ arguably resembling a life reduced to mere existence. Moving into the post-COVID world, we must critically appraise our condition. This essay attempts perspectives on some of the political implications of COVID-19. Through a consideration of ancient philosophies of the likes of Plato and Aristotle, the justification for the institution of the State and why humankind resorts to it, especially in times of crises, has been established. Further consideration of the State’s responses to past global crises, of the Spanish Flu and the Influenza Pandemic, help one understand how such an institution often rules out political concerns and motivations, as opposed to serving the ‘common good’. This is followed by a discussion of the advent of contemporary authoritarianism in the post-COVID world and on the ideology of populism. The concluding part of this essay deliberates on the political landscape of the post-COVID world. While the authors are in no position to conclusively lay down what the post-COVID world will bring forth, they encourage viewing the pandemic as an opportunity to re-evaluate our political choices and rediscovering the power of mutual aid and solidarity as we refuse to return to ‘normal’, rather than treating COVID-19 as an irreversible setback for political rights and emancipation. Humankind must thus climb up the down staircase in approaching the post-COVID world.
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