Introduction: Oral potentially malignant disorders (OMPDs) include leukoplakia, erythroplakia, oral submucous fibrosis, tobacco pouch keratosis. Most of Oral Potentially Malignant Disorders are asymptomatic in early stages which are not observed by the patients, only dental practitioners reported on routine oral examination. These OMPDs lesions are very enigmatic to differentiate from other conditions only by conventional white light examination. Various investigations are utilized for early detection which has certain limitations. The current non-invasive light-based diagnostic tool which focuses on tissue autofluorescence evaluates early mucosal changes and helps to rule out suspicious precursor lesions. Case report: This paper aims to report the cases of OPMDs by using a light-based device called OralID to differentiate between normal and dysplastic tissues. Conclusion: As we know the early detection of oral cancer can increase the higher chance of survival rate compared to advanced stages. This makes timely diagnosis and treatment play a critical role in the lives of patients.Tissue fluorescence technology aids as the gold standard for early detection of abnormal tissue changes when combined with traditional examination of oral mucosa and also helps to differentiate between normal and abnormal tissue.
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