This study investigates air pollution dispersion in urban areas by means of Computational Fluid Dynamics (CFD). The commercial CFD software FLUENT was used to implement two different turbulence simulation methods (RANS and LES), in domains similar to complex urban environments. Particularly, different combinations of roof shapes were studied and simulation results of pollutant (ethane) concentrations were compared against experimental data. The building height (H) to the neighbour building distance (B) ratio was also taken into consideration. Previous studies showed that both RANS and LES models are accurate enough to predict pollutant concentrations fields in B/H = 1. In the present study the incapability of RANS models to predict accurately pollutant concentration in B/H = 0.5 for all roof shapes configurations is revealed.