Two polymorphic hydrogen peroxide solvates of 2,4,6,8,10,12-hexanitro-2,4,6,8,10,12-hexaazaisowurtzitane (CL-20; wurtzitane is an alternative name to iceane) were obtained using hydrated α-CL-20 as a guide. These novel H O solvates have high crystallographic densities (1.96 and 2.03 g cm , respectively), high predicted detonation velocities/pressures (with one solvate performing better than ϵ-CL-20), and a sensitivity similar to that of ϵ-CL-20. The use of hydrated materials as a guide will be important in the development of other energetic materials with hydrogen peroxide. These solvates represent an area of energetic materials that has yet to be explored.

Two polymorphic hydrogen peroxide solvates of 2,4,6,8,10,12‐hexanitro‐2,4,6,8,10,12‐hexaazaisowurtzitane (CL‐20; wurtzitane is an alternative name to iceane) were obtained using hydrated α‐CL‐20 as a guide. These novel H2O2 solvates have high crystallographic densities (1.96 and 2.03 g cm−3, respectively), high predicted detonation velocities/pressures (with one solvate performing better than ϵ‐CL‐20), and a sensitivity similar to that of ϵ‐CL‐20. The use of hydrated materials as a guide will be important in the development of other energetic materials with hydrogen peroxide. These solvates represent an area of energetic materials that has yet to be explored.

A new series of (E)-pyrene oxime ester conjugates of carboxylic acids including amino acids were synthesized by coupling with an environment sensitive fluorophore 1-acetylpyrene. (E)-Pyrene oxime esters exhibited strong fluorescence properties and interestingly their fluorescence properties were found to be highly sensitive to the surrounding environment. Direct irradiation of the (E)-pyrene oxime esters by UV light (≥350 nm) resulted in both the photo-Beckmann rearrangement product and products resulting from N-O bond homolysis. Photoproduct formation and their distribution were found to be solvent dependent. Further, we also showed (E)-pyrene oxime esters intercalated into DNA efficiently and photo-cleaved DNA. Finally we also showed these oxime esters can permeate cells efficiently and may cause cytotoxicity upon irradiation of light.

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