IntroductionAmong head and neck cancers, those of the oral cavity and oropharynx are the second most prevalent following the larynx. This study aimed to research immunohistochemical expression of survivin, HPV positivity and microvessel density in tumors and their relationships with prognosis.Material and methodsPathological materials and demographic properties of 46 patients were retrospectively evaluated. Survivin, HPV and CD34 (for microvessel density evaluation) antibodies were applied tumoral tissues. Survival times, clinical stage and differentiation were evaluated.ResultsIn univariate analysis, we observed that survivin, microvessel density and stage were significantly associated with survival time (p < 0.05). In multivariate analysis, only survivin and microvessel density were associated with survival time (p < 0.05). But we did not find significant correlation between neither tumor differentiation nor HPV positivity and survival (p > 0.05).ConclusionsSurvivin levels and microvessel density were found to be effective prognostic factors and were related to survival in oral cavity and oropharyngeal cancers. Treatments targeting survivin expression and angiogenesis might be employed against these tumor groups.

Understanding the diagnostic imaging studies of the pelvis requires a comprehensive knowledge of the normal and variant anatomy of this region.Computerized tomography (CT) and magnetic resonance imaging (MRI) can be useful for cases with sonographically complicated or discordant clinical findings.Magnetic resonance imaging has advantages in pelvis because of its superior tissue contrast and nonionizing technique.Right and left coxae, sacrum, and coccyx form the bone boundaries of the pelvis and it involves the structures of gastrointestinal and genitourinary system such as rectum, ureters, and bladder. Prostate, vesicula seminales, prostatic urethra, ductus deferens, ductus ejaculatorius in males; uterus, ovaries, tuba uterina, and vagina in females are the other structures located in the pelvis.

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