Transcatheter PDA closure has gained acceptance over surgery because of its cosmetic benefits, shorter hospital stay and absence of pain associated with a thoracotomy. The Amplatzer Ductal Occluder II (ADO II) device provides a solution for the closure of small to moderate-sized PDAs To describe early single-centre clinical experience withADO II.Children with a haemodynamically significant patent ductus arteriosus (PDA) who underwent percutaneous trans-pulmonary closure with Amplatzer Ductal Occluder II (ADO II) were included. Data was collected from computer based patient records.Trans-pulmonary PDA closures using ADO II were undertaken in 65 children (46 females) with a mean age of 2years 3 months (range 5 months to 14 years) and a mean weight of 9.6kg (range 4.2-25kg).Complete occlusion was noted pre-discharge in 64 (98.4%) patients. One (1.6%) had residual shunting after deployment followed by embolization to the left pulmonary artery on the third day of the procedure. Of the 65 children, five (7.7%) had mild flow acceleration in the left pulmonary artery and another one (1.6%) had mild aortic flow obstruction following the procedure.At 7 and 30 days, echocardiography confirmed complete ductal occlusion without need for further intervention in all 64 (98.4%) successful cases.ADO II is highly effective in rapid occlusion of morphologically varied small to moderate-sized PDAs.Ductal occluder; patent ductus arteriosus; trans-pulmonary; residual shunting) Catheterization and Cardiovascular Interventions et al.

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Objective: To describe early single-centre clinical experience with the Amplatzer Ductal Occluder II (ADO II).Method: Children with a haemodynamically significant patent ductus arteriosus (PDA) who underwent percutaneous trans-pulmonary closure with Amplatzer Ductal Occluder II (ADO2) were included. Data was collected from computer based patient records.Results: Trans-pulmonary PDA closures using ADO 2 were undertaken in 32 children (22 females) with a mean age of 1year 9 months (range 5 months to 10 years) and a mean weight of 8.2kg (range 4.2-25kg). Complete occlusion was noted pre-discharge in 31 (97%) patients. One (3%) had residual shunting after deployment followed by embolization to the left pulmonary artery on the third day of the procedure. One (3%) had mild flow acceleration in the left pulmonary artery and another (3%) had mild aortic flow obstruction following the procedure. At 7 and 30 days, echocardiography confirmed complete ductal occlusion without need for further intervention in all 31 (97%) successful cases.Conclusion: ADO II is highly effective in rapid occlusion of morphologically varied small to moderate-sized PDAs.

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