Background and aim: To conduct a descriptive review and synthesize data from all studies assessing the knowledge, attitude, practice, and adverse events of insulin administration and storage techniques in patients with diabetes in India. Methods and Materials: Literature search regarding the knowledge, attitude, practice, and adverse events of insulin administration were performed using the Google Scholar search engine as well as Pub Med up to December 2021. Results: A total of 14 studies were selected which were published from 2014 to 2021. About six of the studies was cross-sectional and the other six of them included cross-sectional, observational survey through a questionnaire. The sample size was around 55-750 and the age range was 30-70 years. A higher level of knowledge and economic status improved insulin administration among the patients. The younger population had a more positive attitude towards insulin administration than the older patients. Insulin practices as well as the adverse events followed by the insulin administration were assessed. Conclusion: The study is a review to examine the knowledge, attitude, practice, adverse events, and storage of insulin among diabetic patients. Diabetes education must be provided to patients as well as health care providers for improved clinical practices of insulin.