A balanced microbiota composition is requisite for normal physiological functions of the human body. However, several environmental factors such as air pollutants may perturb the human microbiota composition. It is noticeable that currently around 99% of the world’s population is breathing polluted air. Air pollution’s debilitating health impacts have been studied scrupulously, including in the human gut microbiota. Nevertheless, air pollution’s impact on other microbiotas of the human body is less understood so far. In the present review, the authors have summarized and discussed recent studies’ outcomes related to air pollution-driven microbiotas’ dysbiosis (including oral, nasal, respiratory, gut, skin, and thyroid microbiotas) and its potential multi-organ health risks.

Indoor air cleaning interventions such as bipolar air ionizers have increased lately due to rampant air pollution and the COVID-19 pandemic. Hitherto, the bipolar air ionizer efficacy against particulate pollutants and byproduct ozone emission has not been fully understood and remained a critical concern. Currently, available diverse and complex methods are insufficient to determine commercially available bipolar air ionizer reliability. The National and International market of bipolar air ionizers is proliferating, while safety standards and information are comparatively limited, in such cases, any misleading information by manufacturers could be detrimental to consumers. To focus on those gaps, the present study comprised five different types of commercially available bipolar air ionizers labeled as BAI 1, BAI2, BAI3, BAI4, and BAI5, which were examined against the most concerned indoor particulate pollutants and potential byproduct ozone. Seven days of consecutive experiments were performed in five acrylic boxes, each box assembled with a testing bipolar ionizer model, calibrated air quality monitor, and particulate pollutant source (incense sticks). Two runs/day for each individual bipolar ionizer were performed for up to seven consecutive days. Overall performance was procured from the daily cumulative arithmetic average. All tested bipolar air ionizers models showed notable, up to 80% particulate matter (PM 2.5 and PM 10 ) removal efficiencies. The highest particulate matter removal was associated with bipolar air ionizers model 4 (PM 10 79.7%, PM 2.5 80.4%) and the minimum with BAI model 5 (PM 10 72.2%, PM 2.5 72.3%). Abnormal ozone emission was not observed with any bipolar air ionizer conduction in this study. Almost negligible elevation in background temperature (0.4 °C) and relative humidity (0.6%) were also observed. In conclusion, bipolar air ionizers could be byproduct ozone-free, indoor particulate matter removal, and low maintenance indoor air cleaning option.