No abstract

To identify the most common cause and the frequent stage of presentation in patients with neovascular glaucoma. Materials and Methods: The present study is a prospective observational study. 136 eyes of 109 patients having neovascular glaucoma in one eye or both the eyes were included in the study. All patients underwent thorough ocular examination i.e., visual acuity, slit lamp bio-microscopy, intraocular pressure (IOP) measurement by Goldmannapplanation tonometry, gonioscopy with Posner 4 mirror indirect gonioscope and dilated fundus examination. Neovascularization of iris (NVI) was identified in an undilated state, presence of any ectropionuveae, hyphema, anterior chamber reaction, pseudoexfoliative material, keratic precipitates and other signs of uveitis were noted. The number of quadrants of the angle having neovascularization was noted. Results: The mean age was 57.59 ± 12.6 years, 80.73% were males and 19.26% were females. Mean IOP was 27.14 ± 11.3 mm of Hg. 74 (54.4%) presented in rubeosisiridis stage, 38 (27.9%) in angle closure stage and 24 (17.6%) in open angle stage. 89 (65.4%) had diabetic retinopathy in variable severity, 16 (11.7%) had uveitis and 14 (10.2%) had retinal vein occlusion. Mean IOP angle closure stage was found to be 36.53±16.259 mm of Hg which is significantly higher than the other two stages (P = 0.000) Conclusion: In the present study, it was found that Proliferative diabetic retinopathy is the most common cause and rubeosisiridis is the most common stage of presentation in NVG.

We studied the clinical profile of patients with raised intraocular pressure (IOP) in closed globe injury and outcome of medical and surgical management.: A prospective, interventional study of 32 patients diagnosed with raised IOP following closed globe injury, who presented to a tertiary care centre during the period of November 2018 to May 2020. Most patients (59%) were young, age group of < 40 years. 71.9% were males. Left eye was involved in 53.1%. Mean duration of presentation after injury was 4.38 days. Most common mode of injury was industrial accidents (28%). Mean IOP at presentation was 29.19 ±7.342. Vision at presentation was ≤ 6/60 in 18.75%. Anterior segment injury was most common. On gonioscopy, 13 eyes (41%) had open angles, 1 eye (3.1%) had closed angle and deferred in rest. Angle recession was present in 2 eyes. 3% of eyes had increased cup-disc ration (CDR) > 0.7. 68.75% were managed medically and 31.2% surgically. In the medical group, mean initial IOP was 26.18±5.124 mm Hg and at 12 months was 14.83 ± 2.287 mm Hg (p <0.0001). A 44% reduction of IOP seen. The initial and final IOP in surgical group was 35.80±7.330 and18.60 ±3.777 respectively with a (p < 0.0001). A reduction of 48% IOP was seen at the end of 12 months in surgical group. There was no significant difference between medical and surgical intervention. There was no significant difference between medical and surgical intervention while treating glaucoma secondary to closed globe injury.