Objectives: The outbreak of COVID-19 has brought about fear and uncertainty resulting to stigmatization and discrimination towards those with COVID-19 like symptoms as well as influence the patient influx to health facilities and the health-seeking behaviour of the population. This study assessed the health-seeking behaviour, hospital attendance, and the level of stigmatization of the population towards individuals with COVID-19 like symptoms. Methods: This was a cross-sectional community and hospital-based study carried out to assess hospital attendance, perceived stigmatization and population health-seeking behaviour during the COVID-19 pandemic in the Buea Municipality. The trend in the patients' influx in the COVID-19 treatment centre and other health facilities was assessed from March to June 2020 and compared with corresponding months in 2019. The stigmatization data was collected using a modified 12-items stigma scale. The data was analyzed with SPSS version 26. Results: The hospital attendance decreased in the COVID-19 treatment centre from April to June 2020 by -38.3% and increased in non-COVID-19 treatment health facilities by over 70%. Of the 570 participants for the community survey, 322 (56.5%) reported to go for auto medication if they developed COVID-19 symptoms. Individuals with COVID-19 like symptoms experienced moderate (59.1%) to severe (33.9%) perceived stigmatization. Perceived stigmatization was significantly higher (χ 2 =14.56, p=0.001) in participants who reported not willing to go to the hospital during the pandemic. Conclusion: The hospital turnout experienced a drop in the COVID-19 treatment centre and an increase in other health facilities. There was high perceived stigmatization towards people with COVID-19 like symptoms, which probably accounted for the population refusal to seek treatment in the COVID-19 treatment center and to resort to auto medication.