Abstract. Soil erosion is one of the most critical environmental hazards that causes land degradation and water quality challenges. Specifically, this phenomenon has been linked, among other problems, to river sedimentation, groundwater pollution and flooding. This paper assesses the susceptibility of Orashi River Basin (ORB) to soil erosion for the purpose of erosion control measures. Located in the South Eastern part of Nigeria, the ORB which covers approximately 413.61 km 2 is currently experiencing one of the fastest population growth rate in the region. Analysis of the soil erosion susceptibility of the basin was based on four factors including; rainfall, Land use/Land cover change (LULC), slope and soil erodibility factor (k). The rainfall was assumed to be a constant and independent variable, slope and soil types were categorised into ten (10) classes each while the landuse was categorised into five classes. Weight was assigned to the classes based on the degree of susceptibility to erosion. An overlay of the four variables in a GIS environment was used to produce the basin susceptibility to soil erosion. This was based on the weight index of each factors. The LULC analysis revealed that built-up land use increased from 26.49 km 2 (6.4 %) in year 1980 to 79.24 km 2 (19.16 %) in 2015 at an average growth rate of 1.51 km 2 per annum while the light forest decreased from 336.41 km 2 (81.33 %) in 1980 to 280.82 km 2 (67.89 %) in 2015 at an average rate 1.59 km 2 per annum. The light forest was adjudged to have the highest land cover soil erosion susceptibility. The steepest slope ranges between 70 and 82 • (14.34 % of the total land area) and was adjudged to have the highest soil susceptibility to erosion. The total area covered of the loamy soil is 112.37 km 2 (27.07 %) with erodibility of 0.7. In all, the overlay of all the variables revealed that 106.66 km 2 (25.70 %) and 164.80 km 2 (39.7 %) of the basin has a high and very high susceptibility to soil erosion. The over 50 % high susceptibility of catchment has serious negative implications on the surface water in terms of water quality and downstream siltation with great consequences on biodiversity and ecosystem services including domestic and industrial usage.