The study was undertaken to determine the level of knowledge of the causes, risk factors and preventive measures of prostate cancer among male teachers in Awka South Local Government Area of Anambra State Nigeria. The population of the study consisted of 200 male teachers in government secondary schools in Awka South Local Government Area. A sample of 100 male teachers was selected using the proportioned stratified random sampling techniques. To guide this study, three specific objectives with corresponding research questions were formulated. Data was collected using Likert scale questionnaire which consisted of 16 items. According to findings, male teachers in Awka south Local Government Area have high level of knowledge regarding prostate cancer, moderate level of knowledge on causes and high level of knowledge and practice of prostate cancer preventive measures. It was recommended that prostate cancer programs should be mounted at different settings where male teachers can be reached.