Objective: The practice of diabetes self-care behaviors has been cited as a foundation for achieving optimal glycemic control. Proper motivation of people with diabetes mellitus is, however, needed for the performance of these behaviors. It is therefore pertinent to know if motivation by the family will improve glycemic control in people with type 2 diabetes mellitus. This study aimed to investigate the relationship between glycemic control and perceived family support among Nigerians with type 2 diabetes mellitus. Methods: A cross-sectional study was conduced on 316 adults with type 2 diabetes mellitus who attended a medical outpatient clinic. Data were collected through a pretested intervieweradministered questionnaire and a standardized tool (Perceived Social Support-Family scale). Hemoglobin A 1c level was used as an indicator of glycemic control. Results: The proportion of participants with good glycemic control was 40.6%. Most of the participants (137, 43.8%) had strong perceived family support. Strong perceived family support (P = 0.00001, odds ratio 112.51) was an independent predictor of good glycemic control. Conclusion: This study shows that strong perception of family support is a predictor of glycemic control among the adults with type 2 diabetes mellitus studied. Physicians working in sub-Saharan African countries with rich kinship networks should harness the available family support of people with type 2 diabetes mellitus in their management.