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Scintillation scans of the joints were obtained after intravenous injection of radioiodine in patients with rheumatoid arthritis, lupus, scleroderma, gout and osteoarthritis. Distinct radioactivity (correlated with the severity of the disorder) was observed in the first four diseases, but not in osteoarthritis. In a 72‐year‐old man with prostatic carcinoma and back pain, x‐ray examination of the lumbar region failed to reveal metastases, whereas they were indicated by strontium85 scanning of that area and confirmed at autopsy. Thus scintillation scanning after the injection of a suitable isotope can be of value in differential diagnosis and in estimating the severity of disease. However, the scan must always be interpreted in the light of the clinical situation.

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