1 The serum lithium concentration was measured before dosing, and at 2, 4, 6, 8, 10, 20, 22, and 24 h after three proprietary preparations of lithium carbonate (Camcolit, Phasal or Priadel). 2 A total of twenty‐ eight studies were performed on eleven patients. In seven studies the patients received Camcolit, in ten studies patients received Priadel and in eleven the patients took Phasal. 3 The dose of each preparation was adjusted during a 10 week run‐in period to maintain the serum lithium within the normal therapeutic range (0.6‐1.2 mmol/1). Five patients received one lithium preparation, one patient received three lithium preparations and five patients received four lithium preparations consecutively. 4 After a single daily dose of Phasal and Priadel, the serum lithium remained within the therapeutic range for 24 h. 5 After a single daily dose of Camcolit, the serum lithium remained within the therapeutic range for only 12 h. 6 After three doses of Camcolit (given at 0.800 h, 12.00 h, and 18.00 h) each day, the serum lithium was maintained in the therapeutic range for 24 h.

Sodium starch glycolate (SSG) is most widely used excipient in the field of pharmaceutical sciences. SSG is extensively used as a superdisintegrant in different drug formulations. This review article aims to discuss chemistry, synthesis, level used as superdisintegrant, different types of SSG’s and various physicochemical properties. SSG available as different brands i.e Primojel, Explotab and Vivastar with different properties. Excipient, generally considered as an inert component, are of great importance in drug product development. Interchange between different suppliers can lead to final products with different quality attributes