Background: The present review aims to examine the way an exercise-based cardiac rehabilitation program affects the cardio metabolic risk profile at patients after Myocardial Infarction. Methods: PubMed/Medline and Scopus/Elsevier electronic databases were searched for studies with no publication date limitation. A search strategy was developed based on the intersection of 2 search themes: cardio logical rehabilitation program and cardio metabolic risk profile. Results: The articles that finally met all the inclusion criteria and were analyzed, after the screening of the title, the summary, and the whole text, were 4. A total of 126 patients after myocardial infarction who received exercise-based cardiac rehabilitation were examined at this review. Conclusion: The present review has demonstrated that exercise-based cardiac rehabilitation improves physical activity levels and the cardiometabolic profile at patients after myocardial infraction. All the existing literature showed improved results, such as reduction in body weight, increased HDL, improved blood pressure and exercise capacity. The program presented better results compared to classic exercise programs.