The novel Nano-catalyst (PAni-Mn) as the first multifunctional catalyst is described for efficient synthesis of α-Aminophosphonates by Kabachnik-Field reaction. This reaction is a Multicomponent reactions in which three- components i e. substituted aldehyde, aniline and dialkylphosphite are combining to form α-Aminophosphonates. The four α-Aminophosphonates were synthesized in good to high yield under solvent free condition at room temperature. The novel Nano-catalyst i.e. Doped Polyaniline with Manganese (PAni-Mn) has been synthesized first and characterized by elemental analysis FT-IR, SEM, TEM, X-ray diffraction technique. This catalyst provides high surface area, increase catalytic activity, easily separated and recycled. It increases the yield of α-Aminophosphonates. α-Aminophosphonates are bioisosteres of amino acids analogous, which has important application in Industrial, Agricultural and Medicinal field, due to their biological and physical properties, They are also use full as synthetic intermediates..

The paper addresses the need for automation in production line. A detailed evaluation of various components required for converting a manual bearing vibration testing machine to an automatic one is carried out. Function and Description of each component is studied. The components include conveyor belts, laser Doppler vibro meter, pneumatic system, mechanical probe, timing and control sensors, speed control system, data analysis and storage unit. A method of selecting each component for automatic vibration testing machine is offered. Based on the structure of automated machine the initial set of alternate variants is defined and a formal model of automatic vibration testing machine is developed. Design of conveyor belt, linear drives, pneumatic system, isolation pad, PLC and HMI system is discussed below. Analysis of supporting structure of Vibration Testing Machine is done using ANSYS 18.1 and results are shown.

α-Aminophosphonate and their derivatives are biologically potent and have received considerable attention in a recent research scenario. The main reason is that they show triguing biological activity. α-Aminophosphonate derivatives are gaining a lot of importance in medicinal chemistry due to their application as enzyme inhibitors, herbicides, antibiotics, pharmaceutical agents and inhibitors of Excitatory Post-Synaptic Potential(EPSP) synthesis, and HIV Protease. It is also important in ati-cancer, anti-HIV, antithrombotic and antibacterial, antioxidant activity. Unfortunately, these compounds have certain limitation such as extraction, purification, of bioactive molecule and their minimum yields. For this reason, many scientists have been orienting their research towards the synthesis of molecules as a new tool to overcome this problems he prime focus of this work is the combination of three reactant derivative of benzaldehyde derivative of aniline, and diethyl phosphonate to form α-aminophosphonates derivatives by multicomponent reaction(KFR). The novel nano-catalyst i.e. polyanilinedoped with manganese (PAni-Mn) was prepared. The catalyst shows excellent catalytic activity, high yields, short reaction times, easy synthesis. The PAni was fully characterized by X-ray diffraction, TEM, SEM, and FT-IR technique.