The present report deliberates the safe handling of prescription containing the narcotic substances and habit forming drugs. This work is confined to the boundaries of Karad and Umbraj city of satara belonging to Indian state of Maharashtra. Here, we attempted to comprehend the proper handling of prescription containing the narcotic substances and habit forming drugs. For the purpose we met with the various retail pharmacist who discussed about proper handling, dispensing and record maintenance of prescription containing narcotics and habit forming substances. Indeed, the information provided by them is crucial and speculates about a pharmacist perspective while handling prescription encompassing narcotics.