Objective: to recognize an alternate method for screening neonatal sepsis in patients while considering the sensitivity and accuracy of the diagnosis. Study Design: Cross sectional study. Place and Duration of Study: Combined Military Hospital, Rawalpindi Pakistan, from Jun to Dec 2021. Methodology: Patients admitted to the Neonatal Intensive Care Unit of the Combined Military Hospital were included in the study. Demographic data, including age, weight, gender, and gestational age, were recorded. In addition, a statistical comparison of total leucocyte count, absolute neutrophil and lymphocyte counts, neutrophil-lymphocyte ratio, and C-reactive protein test was carried out for the cases and controls. Results: It was evident from the results that a significant correlation between the neutrophil-lymphocyte ratio and neonatal sepsis exists. The mean NLR in non-septic individuals was (1.8±1.3) and in septic individuals, it was (2.9±1.9). The p-value was 0.001. Furthermore, ROC showed that at an NLR value of 1.6, sensitivity was 0.594 and 1-specificity 0.295. Conclusion: Neutrophil lymphocyte ratio was an efficient screening tool for determining sepsis in neonates, with comparable results to the C-reactive protein test.
Objective: To Monitor the effect of electrolyte addition in fluids to reduce mortality in neonates and reduce the days of hospital stay. Study Design: Case Control study. Setting: Aziz Bhatti Shaheed Hospital, Gujrat. Period: January 2017 to December 2018. Material & Methods: Babies inborn during the study period of gestational age between 32 to 36 weeks and birth weight range from 1.5 to 2 kg were included in the study. To compare the effect of potassium in both groups, SPSS analysis was carried out. Results: The study resulted in decreased mortality rate with a p value of 0.006. The overall hospitalization time was also reduced presented with early discharge from the hospital setting. Conclusion: The study concluded that early administration of potassium through intravenous fluids demonstrated a rapid recovery and decreased hospitalization of the infants.
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