With recent advancement in medical education importance is given to evaluation, which has been included as a part of curriculum planning and implementation. By finding out the factors that inhibit the successful implementation of curriculum better outcomes can be achieved. A mixed method study was carried out at Dental college HITEC IMS. The study was conducted in two phases. In the 1st phase the quantitative assessment was carried out to find out the success of curriculum and identifying the factors that hindered in its success. In the second phase group discussion for amending the inhibitors was carried out. this study on a validated questionnaire that was prepared on scoping review and Delphi study. Under six themes inhibitors were found in five themes. No inhibitor was found under the theme of educational program. This study has helped us to pick up the inhibitors of curricular success so that we can look into possible solutions to improve the quality of curriculum of dental college. We look forward to help other institutes who are facing the same issues in their curriculum quality by suggesting solution options obtained from focused group discussion. Keywords: Curriculum viability, curriculum inhibitors, dental curriculum

Objective: To see the prevalence and risk factors for post full vaccination (Sinopharm and Sinovac COVID-19 vaccines) weak immunity in persons with no history of viral exposure. Study Design: Prospective Observational. Setting: Syed Research Centre, Sialkot. Period: Nov 2021 to Feb 2022. Material & Methods: Eighty two individuals (male/female, aged: 24-70 years) were enrolled from District Sialkot (Pakistan). Two doses of Sinopharm or Sinovac COVID-19 vaccine were administered to each participant before blood sampling. The quantity of COVID-19 spike immunoglobulin G against SARS-CoV-2 (5-Antigen) was detected in serum using chemiluminescence immunoassay technique [threshold titer: 7.1 (detection), 105. 63 (seroprotection), 492.96 BAU/mL (strong humoral response)]. Results: Overall, 96.3% seropositivity, 89% seroprotection, and 37.8% (n = 31) weak immune response were recorded. Whereas, mean antibody titer was found to be 2312.02 (range: 0.0 – 28711.74) BAU/mL. A vaccinated male had approximately 4 folds (95%CI: 1.297 – 11.504; p = .002) more likelihood of weak immune response than females. Similarly, the rate of poor immunological outcome was higher in individuals with >24.9 Kg/m2 (69.2%, n = 27) body mass index compared to ≤24.9 Kg/m2. A person with Sinopharm COVID-19 vaccine was more vulnerable to weak immune response than Sinovac vaccinated participants (RR = 2.351; 95%CI = 1.327 – 4.167; p .002; 57.6% vs. 24.5%, respectively). Co-occurrence of age (>47 years) and BMI (>24.9 Kg/m2) existed in 11 of 28 males (39.3%) with impaired immunogenicity. Conclusion: The high rate of post full vaccination weak immune response is alarming. Gender, BMI, and vaccine type were amongst the predictors for diminished humoral response.