Congenital Heart Disease (CHD) is the most prevalent birth defect, with an incidence of approximately 8 per 1000 births. Multiple factors that impact the patient's life and quality of life can cause Congenital Heart Disease to become a chronic condition. It is important to assess the quality of life in children with Congenital Heart Disease (CHD) in order to determine whether the child is experiencing quality of life problems and, if so, which aspects are experiencing problems, so that in addition to overcoming the disease, psychosocial impacts and social interactions with other healthy children are avoided. The purpose of this study is to determine the life quality of children with CHD. This study is a systematic review conducted by searching PubMed, Science Direct, Web of Science, and the Cochrane Library. Literature screening was carried out by looking at the predetermined inclusion and exclusion criteria so that 11 literatures were reviewed. Based on the literature study it was reported that the HRQoL scores of children with CHD were at least as good as or comparable to their healthy peers.